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Understanding the Need for Combined Glucose and Ketone Monitoring

For individuals managing diabetes, metabolic health, or ketosis risk, routine self-monitoring has traditionally meant juggling two separate systems. Blood glucose and ketone testing often require separate test strips, separate meters, manual coding, larger blood samples, and limited data connectivity. Each of these steps adds friction: more supplies to carry, more procedures to remember, and more opportunities for error when codes must be entered by hand. For users who need both fasting glucose and ketone tracking—particularly those monitoring metabolic health or ketosis risk—this fragmented approach can make consistent self-monitoring harder than it needs to be.

VivaChek, the brand name used by Weice Biotech, was positioned to address this exact gap. The company’s strategic focus is to provide a one-meter, one-strip dual testing system for blood glucose and β-ketone, built with auto coding and an optional Bluetooth data management feature. This positioning directly responds to the pain points described above: fewer devices, fewer manual steps, and a smaller blood sample requirement.

Technical Design and Core Capabilities

At the center of this approach is the VivaChek Blood Glucose and β-Ketone Dual System, which combines meter and test strip technology into a single point-of-care solution. The system is built on an electrochemical biosensor platform, using glucose dehydrogenase for glucose detection and β-hydroxybutyrate dehydrogenase for β-ketone detection. This dual-enzyme design is what allows one test strip to generate two distinct results from a single fingerstick sample.

The technical specifications reflect a design oriented toward both accuracy and convenience:

• Glucose measurement range: 20–600 mg/dL
• β-ketone measurement range: 0.1–8.0 mmol/L
• Result calibration: Plasma-equivalent, supporting clinical interpretation
• Coding method: Auto-Coding, which automatically reads each test strip’s coding information
• Sample type: Fresh capillary whole blood from the fingertip
• Sample size: About 1.6 microliters
• Testing time: About 12 seconds
• Hematocrit range: 20–65%, which reduces bias across a broader range of users
• Operating temperature: 45.5°F–113°F (7.5°C–45°C)
• Operating humidity: 10–90% R.H. non-condensing
• Test strip storage temperature: 36°F–86°F (2°C–30°C)
• Test strip shelf life: 24 months unopened, 6 months once opened

The meter also includes a rechargeable 250 mAh, 3.7 Volt DC nominal lithium polymer battery with a 5V input charge voltage, charged through a USB Type-C port. An automatic shutoff after 120 seconds of inactivity helps conserve battery life, and the device includes a beep function, a backlight, and a hypo warning feature to alert users to low glucose readings. Test averaging, strip ejector, ketone warning, meal markers, and test alarms are not included in this system.

Analytical Performance

Performance data included with the product shows that meter results clustered along the fitted regression line with strong linearity, an R² greater than 0.96, a slope approximately 1, and no obvious bias. Specifically, glucose results showed good agreement with the comparator method, with an R² = 0.97 and a slope approximately 1. β-ketone results showed an even tighter linear fit, with an R² = 0.996, slope approximately 1, and an intercept approximately 0. These figures point to a system where both analytes—glucose and ketone—track closely with reference measurements across their respective ranges.

Product Features and Daily Use Benefits

The defining feature of the VivaChek Blood Glucose and β-Ketone Dual System is that one meter with one test strip delivers two results—blood glucose and β-ketone—in about 12 seconds. This single-strip, dual-measurement design removes the need for separate strips or meters, directly addressing the supply and cost burden of running two separate testing systems.

Key Features

• Dual measurement: One test strip simultaneously measures blood glucose and β-ketone, consolidating two tests into one action.
• Auto coding: The meter automatically identifies and reads the coding information of each test strip, lowering the risk of coding error that comes with manual entry.
• Wide glucose range (20–600 mg/dL): Covers low to high glucose values in a single measurement window.
• Wide β-ketone range (0.1–8.0 mmol/L): Supports monitoring from normal levels through severe ketosis.
• Small sample size (about 1.6 microliters): A smaller fingerstick sample for routine testing comfort.
• Rapid result (about 12 seconds): Supports timely metabolic decisions without a long wait.
• Wicking action, end-fill sample application: Simplifies how the sample is applied to the strip.
• 300-record memory with date and time: Supports a history of self-monitoring data over time.
• Optional Bluetooth Low Energy version 5.1: Enables data transfer to the VivaChek GlucoKet App for users who want digital record-keeping, directly addressing the connectivity limitations found in more basic systems.

To support interpretation of results, the product materials include reference ranges. For fasting glucose, normal is defined as below 100 mg/dL, prediabetes as 100–125 mg/dL, high as at or above 126 mg/dL, and low as below 70 mg/dL. For β-ketone, normal is below 0.6 mmol/L, mild elevation is 0.6–1.5 mmol/L, moderate ketosis is 1.5–3.0 mmol/L, and severe ketosis is above 3.0 mmol/L. These interpretation benchmarks are referenced from the American Diabetes Association’s Standards of Care in Diabetes—2023 and the International Society for Pediatric and Adolescent Diabetes’ Clinical Practice Consensus Guidelines on Diabetic Ketoacidosis and Hyperglycemic Hyperosmolar State.

Delivery and Deployment

The VivaChek Blood Glucose and β-Ketone Dual System is delivered as a hardware meter paired with disposable test strips, with an optional Bluetooth Low Energy companion app connection for users who prefer digital data management. This deployment model keeps the core testing process straightforward—meter plus strip—while offering connectivity as an added option rather than a requirement, so users can choose the level of digital integration that fits their needs.

Market Position and Customer Fit

The system is designed for point-of-care blood glucose and β-ketone monitoring, serving individuals who are monitoring blood glucose and β-ketone levels as part of managing diabetes, metabolic health, or ketosis risk. Its industry adaptation centers on point-of-care use for people who need both fasting glucose and ketone tracking in one workflow, rather than maintaining two separate monitoring routines.

Taken together, the technical design, analytical performance data, and feature set of the VivaChek Blood Glucose and β-Ketone Dual System reflect a product built specifically to simplify metabolic monitoring. By delivering glucose and ketone results from one fingerstick, with fewer supplies, fewer steps, and faster feedback, VivaChek—the brand name of Weice Biotech—offers a dual testing solution designed around the practical realities of everyday self-monitoring.

https://www.vivachek.com
Vivachek Biotech (Hangzhou) Co., Ltd.

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